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A spokesperson for Vital, which represents manufacturers, wholesalers and other businesses in Canada's pharmaceutical supply chain, told CBC that "while shipments have begun, timing for arrival in individual pharmacies may vary as products continue to move through the supply chain and as demand evolves"

The STEP (Semaglutide Treatment Effect in People with obesity) trials showed that participants lost approximately 1520% of their body weight over 68 weeks, with body composition analyses indicating that roughly 2040% of the total weight lost was lean mass

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