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Hydroxyzine is a prescription medication that belongs to a class of drugs known as antihistamines

These findings support the importance of aiming for waist reduction, especially in people with abdominal obesity, said the authors

One of these side effects is weight gain

Given that the glucose-lowering effect of metformin is so strong and is independent of incretin signalling, it might be difficult to detect the beneficial effect of metformin on the incretin axis in human studies

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This means cells respond more aggressively to circulating insulin