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Longer use carries cumulative organ hypertrophy and cancer-proliferation concerns
In some species (rodents, pigs) there are also appreciable amounts of GLP-1 (7-37) which has similar activity to the 7-36 amide
This hasnt been confirmed in humans, but dont use tirzepatide if you have personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2
Nitzan K, Benhamron S, Valitsky M, et al
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