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These finding is not unexpected since GLP-1 may increase natriuresis through the inhibition of many ion exchangers in the tubules which expression decreases with the progression of CKD and interstitial fibrosis and tubular atrophy 33
Weight loss from GLP-1s or otherwise can significantly increase fertility, hence the rise of Ozempic babies. If you dont want to get pregnant, its important to use contraception when you start a GLP-1
Strong lifestyle changes and, for some people, a maintenance dose help reduce that risk
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