It is a naturally occurring antioxidant tripeptide found in human cells that supports detoxification and cellular protection
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Putatively, their reduced levels in the serum and CSF of PD patients suggest a disruption of this metabolic network, leading to weakened antioxidant defences, mitochondrial dysfunction, and increased vulnerability of DA neurons in the SN
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A randomized controlled clinical trial showed supplementation of L-carnitine tartrate (500 mg twice daily for eight weeks) reduces the body mass index, fasting plasma glucose, insulin, and homeostatic model assessment of insulin resistance, when it is administered as monotherapy or in combination with synbiotics (Fallah and Mahdavi et al