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Advise patients on the symptoms of hypersensitivity reactions and instruct them to stop taking RYBELSUS or OZEMPIC tablets and seek medical advice promptly if such symptoms occur [see Warnings and Precautions (5.7)]

From the above, it can be found that the ubiquitin-proteasome system has a dual function in regulating ferroptosis (Table 2)

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123 However, since mDIC also played a crucial role in providing malate for citrate transport required for fatty acid synthesis its deletion in hepatocytes may downregulate the lipogenic pathway