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Individual response varies, and several factors influence treatment success, including adherence, lifestyle habits, underlying medical conditions, and medication tolerance
The mechanisms for GLP-1 mediated diuresis and natriuresis were explained by Crajoinas et al., who reported that these effects were mediated by changes in renal hemodynamics and by downregulation of NHE3 activity in the renal proximal tubule [126]

1059 Assessing linguistic and cultural appropriateness of patient-reported outcome measures (PROMs) for people with a migration background Lisa Stikvoort 1 , Ellen Elsman 2 , Olga Damman 3 , Caroline Terwee 2 , Lotte Haverman 4 1 Amsterdam UMC, Amsterdam, Netherlands, 2 Amsterdam UMC, location University of Amsterdam, Epidemiology and Data Science, Amsterdam, The Netherlands, 3 Amsterdam Public Health Research Institute, Amsterdam, Netherlands, 4 Amsterdam UMC, location University of Amsterdam, Emma Childrens Hospital, Child and Adolescent Psychiatry & Psychosocial Care, Amsterdam, The Netherlands Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :1059 Aims An estimated 27.8% of the Dutch population has a migration background, with many being non-native Dutch speakers