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The first is inconsistency, since stopping and starting or skipping doses interrupts the steady signal this stack depends on

Injections: Most GLP-1s require weekly injections (yikes!), which some patients find inconvenient or uncomfortable

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In endurance events, where glycogen depletion is a limiting factor, maximizing fat utilization can provide a more sustainable energy source, potentially delaying fatigue

"Influence of Dietary Sources of Melatonin on Sleep Quality: A Review"