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Similarly, it contributes to Parkinsons disease (PD) pathophysiology by increasing systemic IL-17A and upregulating its receptor in the brain ( P.g worsens cognitive impairment by disturbing the gut microbiota and hippocampal SCFA signaling (Liu et al., 2025)
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Upon detecting viral DNA in the nucleus, hnRNPA2B1 translocates to the cytoplasm, where it triggers type I interferon (IFN-I) production, thereby suppressing DNA virus infection
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