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Licensed pharmacological options for weight management in the UK include: Semaglutide (Wegovy, 2.4 mg weekly) a GLP-1 receptor agonist licensed by the MHRA for chronic weight management in adults with a BMI 30 kg/m, or 27 kg/m with at least one weight-related comorbidity
9-11 Expected side effects of this class of drugs are mainly focused on the gastrointestinal tract
and individual items related to desire and arousal
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The metabolic shift produces measurable changes in insulin sensitivity, inflammatory markers, triglyceride levels, and appetite-regulating hormones
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