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It also interacts with nuclear receptors in DNA, which causes protein synthesis

With the mechanistic and therapeutic groundwork laid, we will now delve into clinical evidence from major surgical domains examining how these concepts manifest in real-world patient data and trials, and where gaps remain between bench and bedside

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Phosphorylation of p70S6K1 was significantly induced at 48 and 72 h in cells treated with BMS-754807 or GSK1838705A (Fig