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It can be highly activated by various stress stimuli, where it is required for the re-folding of damaged and unfolded proteins generated under stress 43
10.1016/j.physrep.2019.01.008 83 ZhangY.ShangY.InthavongK.TongZ.SunB.ZhuK.et al (2019)
Poor bioavailability is more likely when the compounds violate two or more of the RO5
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Adjuvant Endocrine Therapy for Women With Hormone Receptor-Positive Breast Cancer: ASCO Clinical Practice Guideline Focused Update
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