Animal experiments confirmed that dural injection of bone marrow mesenchymal stem cell-derived exosomes miR-367-3p significantly reduced the expression of EZH2 in spinal cord tissues of EAE mice, increased the expression of SLC7A11, GPX4, GSH, and SOD, decreased the levels of Fe 2+ and MDA, inhibited spinal cord iron deposition, ferroptosis, and inflammation, and alleviated spinal cord injury ( 2+ and MDA levels, while reducing GSH, NRF2, and GPX4 expression, as well as iron reactive element binding protein 2 (IREB2) in optic nerve tissue
-Tocopherol reacts with lipid peroxyl free radicals in the cytosol to form -tocopheryl radicals together with lipid peroxide, preventing the lipid peroxidation of the lipoproteins
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BioMed research international, 2020, 9210261
The level of intracellular cholesterol is regulated through cholesterol-induced suppression of LDL receptor synthesis and cholesterol-induced inhibition of cholesterol synthesis
Only the L-isomer of the glutamate is formed due to the manner in which the glutamate dehydrogenase binds the alpha-ketoglutarate