One risk of taking GLP-1s for weight loss is the unintentional loss of muscle mass (aka lean mass) as you slim down
Seek attention if you experience complete absence of bowel movements for more than a week, severe abdominal pain, vomiting, blood in stool, or signs of intestinal obstruction such as inability to pass gas combined with progressive abdominal distension
Most healthcare providers recommend starting injectable tirzepatide at the standard starting dose of 2.5 mg weekly regardless of your previous ODT dose, since the bioavailability difference means direct dose conversion is not possible
doi: 10.3389/fimmu.2018.02648 86 Rosas-BallinaMGoldsteinRSGallowitsch-PuertaMYangLValdes-FerrerSIPatelNBet al
When intake falls too far, the body reacts defensively by cutting energy spending on functions it treats as non-essential
But part of the problem is also pressure on prices from governments and, in some markets, generic manufacturers