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3g, GS siRNA transfection, which led to more than 60% GS gene silencing, similarly increased the sensitivity of hepatocytes to TNF killing, suggesting that increased GSSG accumulation mechanistically contributed to cellular glutathione imbalance-induced susceptibility to TNF-induced cell death
Prescribers who recommend it over FDA-approved alternatives must document in writing why those alternatives are contraindicated or insufficient for the individual patient
Similarly, metastatic thyroid tissue samples in the GLP-1R-low category had increased immune-related pathway enrichment when compared to samples in the GLP-1R-high category ( Figure 3b )
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