This pattern reflects the chronic, relapsing nature of obesity and has prompted the WHO to recommend continuous, long-term treatment lasting six months or moreeffectively positioning these medications as lifetime therapies for many patients [51]
The maximum dose studied in clinical trials is 12 mg weekly
Yang, R
Diet and exercise remain necessary because they support health, strength, and long-term weight control
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115 Sterols themselves are poorly absorbed from the diet, but because of their chemical similarity to cholesterol, are thought to compete with cholesterol for absorption in the intestines, which has the net effect of reducing LDL levels