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In the SURMOUNT-1 obesity trial, tirzepatide produced mean weight reductions of roughly 1521% depending on dose over 72 weeks ( Jastreboff et al., NEJM 2022

Sarah Ackley, a dementia epidemiologist at Brown University wasnt surprised by the failure and told Being Patient that people taking GLP-1s tend to be wealthier, healthier and have better preventative care, which means theyre less at risk of Alzheimers

Many patients will not be candidates for this treatment, and that determination is made intentionally, not by default

If you are taking oral medications for other conditions, such as thyroid medication, heart medicine, or anti-seizure drugs, fiber can potentially interfere with how those pills are absorbed

Morning after using the bathroom, before eating or drinking, is the most consistent approach