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The morphology of mitochondria was studied by transmission electron microscopy (TEM) using a Hitachi TEM system (HT7800, Tokyo, Japan)

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Additionally, obesity itself can contribute to gut dysbiosis, creating a vicious cycle

This shows that natural homocysteine levels are a U-shaped curve in regard to all-cause mortality, but if there is an external reason for low homocysteine, such as excess NAC or B6, there is no statistically significant negative effect.[ref] Which brings us to the role of the gut microbiome in both low or high homocysteine

At the translational clinical level, L-carnitine primarily targets hepatic steatosisthe earliest pathological step in MASLD