2021;96(16):e2098108
But why is there even a need for such a medication
Dietary Fiber Intake and Gut Microbiota in Human Health
J Periodontal Res 54:106114 Zhai S, Liu C, Vimalraj S, Subramanian R, Abullais SS, Arora S, Saravanan S (2023) Glucagon-like peptide-1 receptor promotes osteoblast differentiation of dental pulp stem cells and bone formation in a zebrafish scale regeneration model
N Engl J Med 377:644657 Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A, Silverman MG, Zelniker TA, Kuder JF, Murphy SA, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Ruff CT, Gause-Nilsson IAM, Fredriksson M, Johansson PA, Langkilde AM, Sabatine MS (2019) Dapagliflozin and cardiovascular outcomes in type 2 diabetes
Only a small fraction, less than 5%, of tryptophan is converted to 5-HT, with the majority being metabolized through the KPthe primary route for tryptophan metabolism (Hglund et al., 2019)