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for those with neurological involvement, 1 mg on alternate days until no further improvement
Intramuscular hydroxocobalamin injections are the recommended first-line treatment in the UK, as they bypass the absorption problem caused by lack of intrinsic factor
Keep the needle in place for a few seconds after injecting to ensure the full dose is delivered
Interactions: Are there concerns with my current medications or conditions
Ozen E, Mihaylova RG, Lord NJ, Lovegrove JA, Jackson KG
The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure
