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Building a multidisciplinary framework Implementing tirzepatide in sleep medicine may require a multidisciplinary approach, ideally involving obesity medicine specialists or clinics, registered dieticians, behavioral health professionals and well-trained administrative staff for coverage navigation
Take home message The OASIS 4 trial demonstrates that oral semaglutide 25 mg produces weight loss comparable to the 2.4 mg injectable dose of Wegovy
Most Americans already fall short of this target even without appetite suppression
A separate Phase 2 trial in people with type 2 diabetes was also published in the NEJM in 2023, reporting meaningful reductions in HbA1c alongside weight loss
Diabetes Care (2015) 38(7):126373.10.2337/dc14-1984 56 HinshawLSchiavonMDadlaniVMalladADalla ManCBharuchaAet alEffect of pramlintide on postprandial glucose fluxes in type 1 diabetes
For guidance on switching between different GLP-1 medications , careful provider oversight is essential
