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Pola P, Tondi P, Dal Lago A, and et al
For those with cardiovascular concerns, this modest reduction can be meaningful
However, this may happen during the first few weeks of the treatment or after a dose increase
Kuhne S
The severity was described as "mostly mild to moderate" in the NEJM publication, with events partially mitigated by the lower starting dose protocol (Jastreboff et al., NEJM 2023)
The process takes about 1520 minutes with minimal discomfort and zero downtime
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