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In cell culture systems, LAC formed in mitochondria is transported into cytosol and enters nucleus becoming a source of acetyl groups for histone acetylation [38]
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Devenport SN, Shah YM
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Approximately 70 cytokines, encompassing interleukins, interferons, colony-stimulating factors, and growth factors, exert their regulatory influence predominantly via the JAK/STAT pathway, serving as the principal mechanism for initiating transcription