While head-to-head comparison is lacking, CagriSema seems more effective in promoting weight reduction than the dual agonist of GLP-1R and gastric inhibitory polypeptide (GIP) receptor, tirzepatide (table 2)
Furthermore, across several cellular models, incretin receptor agonists have been reported to suppress pro-fibrotic signalling pathways, including TGF-/Smad signalling, and NFB activation, leading to reduced expression of ECM proteins
JLJ is a trustee of the American College of Cardiology
Isaac Glatstein works with patients to choose a timeline that balances medication safety with fertility goals, rather than stopping treatment suddenly at the last minute
Feel the Difference: Use 1-2 times daily or as prescribed, and experience results in as little as an hour
Contraception note for tirzepatide Tirzepatide delays gastric emptying and may reduce the effectiveness of oral hormonal contraceptives