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Retatrutide demonstrated greater weight loss than survodutide in their respective Phase 2 trials (24.2% vs 18.7%), likely driven by its unique triple-agonist mechanism that adds GIP receptor activation
Jan 23 2021;397(10271):319-333
Glucagon Receptor Activation The glucagon component is what separates Retatrutide from everything else on the market
[3] This matters enormously for interpretation: a result obtained with CagriSema describes cagrilintide plus a potent GLP-1 analog, and cannot be read as the effect of cagrilintide by itself
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