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If pigmentation is undesirable, reduce dosing frequency to once weekly or lower the dose to 0.5mg
No large randomized controlled trials exist specifically for ondansetron in GLP-1-associated vomiting, but the mechanistic rationale and clinical practice consensus are strong
Nat Cardiovasc Res 3, 431440 (2024)
Body composition support: associated with a better balance between lean mass and fat, supporting body recomposition
Dose escalation also impacts outcomes: while some patients achieve significant weight loss at lower doses, others require higher doses to access the full medication effect
GLP-1 medications work by mimicking the GLP-1 hormone (a satiety-inducing hormone), which signals fullness to the brain, slows gastric emptying, and helps stabilize blood sugar, explains Dr
