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Research published in Nature demonstrates that glutathione neutralizes reactive oxygen species (ROS) by donating electrons to quench free radicals, subsequently being oxidized to GSSG before regeneration by glutathione reductase
Ann Oncol 20:736740 Monk B, Kauderer J, Moxley K, Bonebrake AJ, Dewdney SB, Secord AA, Ueland FR, Johnston CM, Aghajanian C (2018) A phase II evaluation of elesclomol sodium and weekly paclitaxel in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube or primary peritoneal cancer: an NRG oncology/gynecologic oncology group study
Moreover, no significant drug release was observed at the beginning, indicating the stability of the DNZ-NLPs
For a broader orientation to the compound, see our GHK-Cu copper tripeptide research overview
& Szumlanski, C
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