Raeissadat SA, Rayegani SM, Forogh B, Hassan Abadi P, Moridnia M, Rahimi Dehgolan S
Cognitive Enhancement Studies Cognitive improvement studies in 28-month-old mice (equivalent to elderly humans) using 10 mg/kg body weight administered 5x per week for 3 weeks demonstrated: Significantly faster escape hole finding in Box Maze tests (trials 4 and 5) Evidence of decreased brain inflammation Increased histone deacetylase 2 labeling indicating epigenetic pathway activation Preliminary reversal of age-related cognitive impairment Pain and Anxiety Modulation Anti-pain effects in mice at 0.5 mg/kg showed efficacy comparable to cimetidines human analgesic effects, affecting 7 anti-pain genes (increased) and 2 genes (decreased), with upregulated opioid receptors and related pain-modulating pathways
Ever wondered about GLP-1
Wells G, Shea B, OConnell D et al (2004) The NewcastleOttawa Scale (NOQAS) for assessing the quality of non-randomized studies in meta-analysis
yet achieving and sustaining clinically meaningful loss is notoriously difficult
Copper-coordination complex Every batch of GHK-Cu is sent to an accredited independent laboratory before it ships