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Clinical outcomes in t(4;14) multiple myeloma: a chemotherapy-sensitive disease characterized by rapid relapse and alkylating agent resistance
doi: 10.3389/fcimb.2021.630812 Received 18 November 2020 Accepted 05 February 2021 Published 12 March 2021 Volume 11 - 2021 Edited by Justin Boddey, Walter and Eliza Hall Institute of Medical Research, Australia Reviewed by Sandra Duffy, Griffith University, Australia
Indeed, in the presence of CRBN overexpression, ( S )-dHTC1 induces maximal degradation at concentrations spanning more than three orders of magnitude with no apparent hook effect at any time point (Extended Data Fig
A smaller barrel spreads a small dose across more length, making it easier to measure accurately
The study found no impact on folate levels, but reported a 5% reduction in serum B12 levels when women went from 0 to 30 g of alcohol a day
If reaction occurs, that specific formulation should be avoided
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