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Discontinue use if mood shifts appear

What you eat and your overall nutrition status has a profound effect on brain structure and function, affecting markers of neuroplasticity and influencing cognition and mood

For example, Arthrotec, a combination product of diclofenac and misoprostol, is approved for use in osteoarthritis or rheumatoid arthritis patients at high risk of gastrointestinal disorders

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High zinc levels may also interfere with the bodys ability to absorb other important minerals, like copper

doi:10.1016/j.taap.2011.02.006