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Microscopy was performed using a Leica DMi8 microscope (Leica Biosystems, Waltham, MA, USA), and staining in the mouse isocortex and hippocampus regions were quantified using the ImageJ software ( Multiplex assay to quantify cytokines and chemokines The xMAP technology (Luminex Corp.) employs a sandwich immunoassay with fluorescent bead-based technology to interrogate the concentrations of up to 500 target analytes in a single sample

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E., Monterrubio, E., Barquera, S

6 to 20 units per day on a 1 ml insulin syringe, equal to 0.6 to 2 mg per injection

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One prominent mechanism is the downregulation of major histocompatibility complex class I (MHC-I) molecules on tumor cells, which impairs antigen presentation and reduces the visibility of malignant cells to cytotoxic T lymphocytes (36)