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Do not combine any medications without consulting a medical provider first
A notable limitation of these agents is the need for continuous treatment, as discontinuation has been associated with rebound weight gain (56)
Notably, SGLT-2is are medications of small molecular weight, with lower LogP oct than the permeation prediction index of BBB (listed in Table 2)
Certain conditions, such as a history of medullary thyroid carcinoma or pancreatitis, may make this medication unsuitable for you
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With the same doses of semaglutide, there was a resulting 2.1%, 0%, 0%, 2.5%, 4.7%, and 9.1% respective increases in the proportion of patients achieving a 10%, or greater, reduction in weight loss
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