After 5 half-lives, less than 3% of the original dose is left
While the RNI for maintenance is only 1.5 g daily, therapeutic oral doses typically range from: 50-150 g daily for mild deficiency prevention in at-risk groups 1,000-2,000 g daily for treating confirmed deficiency without malabsorption Some formulations contain up to 5,000 g, though there is no proven additional benefit over 1,000-2,000 g for most patients The reason for this dosage discrepancy lies in absorption efficiency
They are not a magic shortcut, nor a substitute for healthy eating, movement, or medical guidance
However, more randomized controlled trials are needed to understand how vitamin B12 impacts vision health
He says that there is another much faster option that could be used in this case: enforcement discretion
If you are deficient, you need to find out why