In the outcome of changes in the total cholesterol levels, low credibility of ICEMAN result shows that L-carnitine supplementation has no difference in changes in NAFLD/duration_12 weeks (MD: 2.5, 95%CI: 14.85 to 9.81) but has significant changes (reduced) in the NASH/duration_24 weeks (MD: 20.7, 95%CI: 28.22 to 13.22)
Clin Nephrol
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Oxidative stress, inflammation, and a decline in mitochondrial function are major contributors to this process
Ethics declarations Conflicts of interest JP has received consulting fees from Kyowa Kirin, Eli Lilly, and Theramex
Starter dose 2.5 mg is on the lower end, maintenance 12.5 to 15 mg is on the higher end