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These data suggests that GSH in the ELF may in fact originate from the plasma and hints at a strong reliance of the lung on the inter-organ supply of GSH especially during oxidative stress

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Since, the latter might have tiny impurities, like particulate matter or other suspended particles, filtration devices are pivotal in removing these unwanted particles from protein solution

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GTP cyclohydrolysase 1 (GCH1), the rate-limiting enzyme for BH4 synthesis, also functions as a free-radical trapping antioxidant to inhibit ferroptosis (Kraft et al., 2020)