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Rogan MT, Staubli UV, LeDoux JE (1997)
Do you know which one won
The intertwined roles of PERK and IRE1 in angiogenesis, EMT, dormancy, and therapy resistance emphasize why indiscriminate UPR inhibition is unlikely to succeed clinically and why pathway-selective, context-aware strategies are needed
A multi-year open-label observational study in elderly patients reported improvements in self-reported sleep quality and physical performance scores, although study designs lacked blinding and modern placebo control
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