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The ECD regions were modelled manually against the ECD- and receptor-focused maps due to the poorly resolved density in the consensus map

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Nimbolide has demonstrated cytotoxic effects on NIE-115 neuroblastoma (mouse), 143B TK-osteosarcoma (human), and Sf9 (insect) cultured cell lines, with IC30 values of 27 and 112 m, respectively [112, 113]