These are illustrative, not a contraindication checklist there is no contraindication table because there is no approved indication: Known or suspected malignancy the proposed pro-angiogenic mechanism (particularly via VEGFR2-Akt-eNOS signaling) raises theoretical concerns about tumor vascularization that have not been characterized in humans Pregnancy or breastfeeding no human reproductive or developmental toxicology data exists Known peptide hypersensitivity or a history of serious peptide-related adverse reactions Athletes subject to anti-doping testing BPC-157 is prohibited by WADA under S0 in-competition and out-of-competition
Brain Sciences (2021) This study by an independent research group (outside the original Washington State University team) demonstrated that Dihexa rescues cognitive impairment in an Alzheimer's disease mouse model (APP/PS1 transgenic mice)
Everything below is drawn from the published studies themselves
Always rotate sites to avoid local irritation
Dose Range: From 0.25 mg up to about 4.5 mg weekly in advanced protocols, increased gradually [1]

It includes 1-5 intramuscular or subcutaneous injections of 1000 mcg crystalline cyanocobalamin daily, followed by oral doses of 1000-2000 mcg/day Parenteral administration should be reserved for those with significant neurological symptoms NICE guideline: Vitamin B 12 deficiency in over 16s: diagnosis and management: Malabsorption as the confirmed or suspected cause of vitamin B 12 deficiency: Offer replacement to people if: lifelong intramuscular vitamin B12 Autoimmune gastritis is the cause They have had a total gastrectomy They have had a complete terminal ileal resection If the person has a vitamin B 12 deficiency because of malabsorption that is not caused by autoimmune gastritis, or a total gastrectomy or complete terminal ileal resection (for example, malabsorption caused by coeliac disease, partial gastrectomy or some forms of bariatric surgery): Offer vitamin B 12 replacement and Consider intramuscular instead of