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The weight-management indication (marketed as Zepbound in the US) is described in 2026 secondary summaries as "available now in the UK" [1][2]

Your clinician will review your medical history and confirm that the treatment is safe and suitable for your individual circumstances

Initial studies in rats caused concerns over GLP-1 RAs causing thyroid cancer, but human studies are less clear on whether it is a concern.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)

Subgroup analyses were conducted according to the type of underlying diseases, type of control, and trial duration

This accounts for roughly half the BP reduction

1.2 g Saturated Fat