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Furthermore, studies have shown that paclitaxel can increase the protein levels of transforming growth factorbetaactivated kinase 1 (TAK1) and TAK1binding protein 1 (TAB1), which are modulators of the JNK pathway, and increase the phosphorylation of JNK and the expression of cleaved caspase-7 and PARP, ultimately leading to the apoptosis of thyroid cancer cells (Yu-Wei et al., 2020)

Wheat allergy is another cause

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