Questions in domain one assessed the randomization process for selecting the subjects in each trial, while domain two reviewed if there were any deviations from the intended interventions
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This was a collagen-production study not a broad wrinkle-reduction trial so the scope matters
95% CI, 0.55-1.23
Moiz A, Filion KB, Tsoukas MA, Yu OHY, Peters TM, Eisenberg MJ