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Baseline characteristics The meta-analysis participants were distributed across different treatment groups: 2820 participants in the combination therapy arm and the rest divided into 37.1% (14,789 participants) SGLT-2i monotherapy, 20% (7965 participants) GLP-1RA monotherapy, and 42.9% (17077 participants) placebo or TAU
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Fumarate is an intermediate compound naturally produced within the Krebs cycle itself
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- January 20, 2026) - Functional Brands Inc
Potential pathways include improvements in endothelial function, reductions in blood pressure, anti-inflammatory effects, and direct myocardial protection, all of which have been described with GLP-1RA therapy independent of weight change [12,13,14]
