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Both peptides increase GH levels, but Ipamorelin is considered more selective and does not significantly affect other hormones such as cortisol and prolactin
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Holst, PYY, a potent appetite regulating hormone that belongs to the neuropeptide Y and pancreatic polypeptide family of peptides, is co-localized with GLP-1 in the L-cells (Holzer et al., 2012)
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