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The extended half-life of approximately 7 days enables once-weekly dosing, making it particularly convenient for sustained research protocols
The interactions between drugs and disease targets were visualized using Venny 2.1 to generate a Venn diagram, revealing 17 drug-disease targets (Figure 5C)
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Merkel et al., 2025) and modulate synaptic input into dopaminergic neurons (Mietlicki-Baase et al., 2013
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![Competitive binding in INS-1 cells of [ 125 I]GLP-1 vs. various](https://www.researchgate.net/publication/51880483/figure/fig1/AS:341707901161477@1458480920372/Competitive-binding-in-INS-1-cells-of-125-IGLP-1-vs-various-exendin-4-analogs.png)
