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(2024), analyzed a substantial US real-world dataset and found that T2DM patients using semaglutide exhibited a 40%70% lower risk of receiving a first-time Alzheimers disease (AD) diagnosis than those on other antidiabetic medications (Wang et al., 2024)

In a large analysis , people with type 2 diabetes who took 1 mg of semaglutide lowered their A1c by an average of 1.77% after 26 weeks compared to 1.09% with the highest dose of metformin

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Its unique -glutamyl linkage rather than the standard -peptide bond between Glu and Cys confers resistance to most peptidases and extends its intracellular half-life substantially

The new blockbuster obesity drugs, made famous by Ozempic, are collectively known as GLP-1 agonists, for the hormone they mimic in the body: glucagon-like peptide 1