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Who may notice the difference most Patients with clearly documented hormone deficiency, menopausal transition symptoms, androgen-related complaints, thyroid overlap, or fatigue that has not responded to basic interventions may be the clearest candidates for benefit
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Valproate must not be used in women of childbearing age unless a pregnancy prevention programme is in place
This could lead to broader changes in population health management and overarching changes in health system needs
This pattern was not observed in the placebo groups fibrinogen levels
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