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Their proximity to enteroendocrine L-cells suggests a potential contribution of lymphoid tissue in GLP-1/GLP-1R signalling, as mediator of L-cell proliferation (59, 60)
Available from: Australian Government, Department of Health
Factors independent of glycaemic and weight loss effects have also been suggested to affect the cardiovascular protective effects of GLP-1RAs
Recent large-scale clinical trials have been conducted to verify the weight loss effects of GLP-1RAs, especially liraglutide and semaglutide, in patients without diabetes [12, 13], which showed statistically significant weight loss when compared with lifestyle modification only
Collagen Protection GHK-Cu inhibits metalloproteinases (MMPs) enzymes that break down collagen and elastin
Diabetologia 2012;55:15771596
