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GH secretagogue comparison Property Class CJC-1295 No DAC GHRH analog CJC-1295 with DAC GHRH analog (binds albumin) Sermorelin GHRH analog Ipamorelin GHRP (ghrelin mimetic) Property Half-life CJC-1295 No DAC ~30 minutes CJC-1295 with DAC 68 days Sermorelin 1020 minutes Ipamorelin ~2 hours Property Dosing frequency CJC-1295 No DAC 13x daily CJC-1295 with DAC 12x weekly Sermorelin 12x daily Ipamorelin 13x daily Property Common dose range CJC-1295 No DAC 100300 mcg per injection CJC-1295 with DAC 1,0002,000 mcg per week Sermorelin 100500 mcg per injection Ipamorelin 100300 mcg per injection Property GH release shape CJC-1295 No DAC Pulsatile, physiological CJC-1295 with DAC Sustained elevation Sermorelin Pulsatile Ipamorelin Brief, selective pulse Property FDA status CJC-1295 No DAC Not approved CJC-1295 with DAC Not approved Sermorelin Previously approved

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This was completely avoided in diazepam+bpc 157 10 microg or diazepam+bpc 157 10 ng chronically treated animals