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Nonetheless, it would be interesting to examine whether or not metformin is able to reverse the decreased sensitivity of pancreatic beta cells to the insulinotropic effects of incretins associated with genetic polymorphisms in TCF7L2 [2830] and WFS1 [31]
Wortelboer, K., et al
It is caused by medication exposure and typically resolves when the offending drug is discontinued
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J Immunol Methods 119:203210
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