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10.1056/NEJMoa1406761 180

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In addition to P2Y 12 , platelets express the P2Y 1 receptor , however, the role of P2Y 1 in platelet activation is not as significant as it is for the P2Y 12 receptor

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Inhibiting NNMT with 5-Amino-1MQ preserves intracellular NAD+ levels, which supports mitochondrial function and has been shown in rodent models to reduce adiposity and improve insulin sensitivity